pentobarbital will decrease the level or effect of linagliptin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. Use of other therapies is strongly advisable when linagliptin would be to be administered which has a CYP3A4 inducerpentobarbital decreases amounts of panobinostat by affecting hepatic/intestinal enzyme CYP3A

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